Clinical application of findings of clinical trials and systematic reviews
نویسندگان
چکیده
منابع مشابه
Clinical application of findings of clinical trials and systematic reviews.
he late Professor Archie Cochrane is probably best remembered for enunciating several key principles which are now recognised as fundamental in all areas of clinical practice and associated research. He insisted on the central role of the randomised controlled trial (RCT) in seeking to evaluate the efficacy of interventions, particularly (though not exclusively) in the clinical context. Since t...
متن کاملClinical Applicability of Stem Cell Therapy in Dental Diseases: A Systematic Review of Available Clinical Trials
Background: Developing cell-based therapeutic methods for the differentiation of various stem cells to the dental tissues could be a revolutionary step towards the use of cell therapy for dental disease. In the present study, we aimed to systematically review the literature to establish the efficiency of stem cells in treatment of various dental diseases. Methods: A literature search was perfo...
متن کاملEvaluation of Clinical Trials
In a number of important clinical issues such as evaluation of the efficacy or effectiveness of therapeutic or preventive interventions as well as for comparing the harms of interventions, randomized controlled trials (RCTs) provide the highest levels of evidence, either directly or indirectly. It is obvious that critical appraisal of these studies to assess their validity and precision is of p...
متن کاملRole of NIHR HTA clinical trials on subsequent systematic reviews
Results The preliminary findings from the Cochrane Library found 28 trials out of the eligible 121 trials (excluding four pilot and feasibility studies) were found in a subsequent Cochrane systematic review. The weight of the included HTA trials varied widely (from 100% to 9%). In eight reviews, the trial had a weight of 100% indicating how the trial provided the only evidence for that particul...
متن کاملClinical relevance of findings in trials of antipsychotics: systematic review.
BACKGROUND There is concern over the methods used to evaluate antipsychotic drugs. AIMS To assess the clinical relevance of findings in the literature. METHOD A systematic review identified studies of antipsychotics that used the Brief Psychiatric Rating Scale (BPRS) and Positive and Negative Syndrome Scale (PANSS). A published method of translating these into Clinical Global Impression - C...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Postgraduate Medical Journal
سال: 2002
ISSN: 0032-5473
DOI: 10.1136/pmj.78.917.129